These sterilisers are fitted with an integrated ventilation system that mixes the clean steam and air together, thus creating the sterilisation medium.

This process method is recommended for complex plastic or glass containers, such as pre-filled syringes or vials in which condensates may form and become problematic for the finished product. The system ensures optimum heat distribution throughout the entire sterilisation phase (temperature deviation below ± 1°C). These autoclaves also boast a better drying process, thanks to the ventilation system that prepares the unloaded product for labelling and packaging.

These sterilisers are equipped with a high-flow water recirculation system, thanks to the centrifugal pumps and “double-head multitube” heat exchangers which allow a “water” medium (WFI or PW) to be used as a means of transferring heat to warm up, sterilise and cool down the load. The system ensures optimum heat distribution throughout the entire sterilisation phase (temperature deviation below ± 1°C). This process method provides for faster cycles but the treated product comes out still damp. Nevertheless, it remains the preferred method in most cases,

due to its simplicity, cost-effectiveness and ease of validation.